Recent advances in cross-coupling reactions in aqueous medium
Keywords:Suzuki-Miyaura, Sonogashira, Heck; cross-coupling, heterogeneous, aqueous-catalysis
Transition metal catalyzed cross-couplings reactions, such as Suzuki-Miyaura, Sonogashira and Heck has emerged as important synthetic route for carbon-carbon bond formations. Various products of these reactions have wide applications in medicinal and pharmaceuticals industries. This review comprises of the use of aqueous media as a greener protocol for organic synthesis that have emerged in recent years.